Single nucleotide polymorphisms in exon 10 of the chinchilla growth hormone receptor (GHR) gene.

نویسندگان

  • Daniel Polasik
  • Marek Kmieć
  • Silvia Liefers
  • Arkadiusz Terman
چکیده

The aim of this study was to detect SNPs in exon 10 of the chinchilla growth hormone receptor gene (GHR) by comparative sequencing. Sixty females of the same breed (Standard) were analysed. Four new SNPs were identified, which cause 3 amino acid substitutions in the intracellular domain of the receptor: G/C at position 135 bp (in relation to the total sequence of exon 10) (gln/his), CAG/AAA at 352 bp and 354 bp (gln/lys), and C/A at 641 bp (thr/asn).

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عنوان ژورنال:
  • Journal of applied genetics

دوره 46 4  شماره 

صفحات  -

تاریخ انتشار 2005